
Substance use prevention focuses on reducing factors that increase the likelihood of problematic substance use while strengthening protective factors such as family connection, healthy coping skills, education and early support. Families can help by talking openly about alcohol and drugs, setting clear expectations, watching for meaningful changes in behavior and seeking professional help when concerns arise.
October is National Substance Abuse Prevention Month, an opportunity to focus on preventing substance misuse before it develops into a more serious problem. SAMHSA now recognizes the observance as Substance Use & Misuse Prevention Month. Effective substance use prevention involves understanding why people may turn to substances and recognizing when someone needs additional support.
Substance Use in America: Current Numbers
The scale of substance use disorders (SUDs) shows why prevention remains important. According to the latest available National Survey on Drug Use and Health (NSDUH), 48.4 million Americans aged 12 and older, or 16.8% of that population, had an SUD in 2024. Among young adults ages 18 to 25, the rate was 25.9%. About 2 million adolescents ages 12 to 17 had an SUD during the same year.
These numbers don’t mean substance use disorder is inevitable. They highlight the value of understanding risks early and creating conditions that can make substance misuse less likely.
Risk Factors for Substance Abuse
There is no single reason why someone develops an SUD. NIDA describes risk and protective factors that operate across individual, family, peer, school and community levels. Some factors can change over time, while others cannot.
Risk may be influenced by:
- Genetic predisposition or a family history of addiction
- Mental health concerns
- Adverse childhood experiences or chronic stress
- Peer groups in which substance use is common
- Easy access to alcohol or drugs
- Low perception of the risks associated with substance use
- Family conflict or a lack of consistent support
Having one or several risk factors doesn’t mean a person will develop an addiction. Instead, these factors can help families understand where additional support may be useful.
Protective Factors That Reduce Risk
Protective factors can counter some risks and support healthier development and decision-making. Factors such as positive self-image and self-control may play a protective role. Prevention can also work across families, schools, peer groups and communities.
At home, practical protective steps can include:
- Maintaining regular communication
- Setting age-appropriate expectations around substance use
- Taking an interest in children’s friendships and activities
- Making room for healthy outlets for stress, including exercise, hobbies, creative activities and supportive relationships
Mental health deserves attention as part of prevention. Substance use and mental health conditions can overlap, making early support for anxiety, depression, trauma or other concerns particularly important.
Early Warning Signs to Watch For
Warning signs vary, and one change in behavior doesn’t prove that someone is misusing substances. Patterns and unexplained changes are more useful to pay attention to.
In teenagers, concerns might include sudden changes in friends, falling grades, unexplained absences, secrecy, loss of interest in usual activities or significant changes in sleep and mood. Adults may begin missing responsibilities, withdrawing from family, experiencing financial problems or repeatedly using substances despite negative consequences.
At work, frequent unexplained absences, declining performance, unusual behavior or repeated safety problems may raise concerns. However, these signs can have many causes. They should prompt a conversation rather than an accusation.
FHE Health’s guide to the signs of addiction provides more detail on behavioral and physical changes that may warrant attention.





