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Drug-related deaths are on the rise in the United States and have become a significant threat to public health in recent years. According to the Centers for Disease Control and Prevention, nearly 107,000 people died from overdose in 2021. This number includes accidental deaths as well as suicidal overdose deaths, and it’s more than double the number of drug-related deaths the CDC reported in 2015.
Drug overdoses are a leading cause of preventable deaths, and every year, hundreds of families and friends are left to deal with the aftermath of these tragedies. Fortunately, there are simple things anyone can do to tackle harmful stigmas and promote access to helpful information and resources for those living with addiction.
What Happens During an Overdose?
Overdoses are complex, and it’s not always clear what pushes the body beyond a high to an overdose. However, there are a handful of factors that may make an individual more vulnerable to overdosing, which is important to keep in mind when spreading overdose awareness. Mixing opioids with sedatives such as alcohol or anxiety medications, using drugs in very high doses, and relapsing after having been in detox are all associated with increased overdose risks.
When someone first takes an opioid, the drug enters their body and travels through their heart and lungs. At this point, it gets flushed with oxygen and then carried back into the heart. From there, it continues to be pumped through the body and gets plugged into the body’s opioid receptors.
Once the drug is carried to the brain, it activates dopamine production. This is what causes the individual to experience a high. Before long, the high evens out, and the individual typically begins to feel sleepy. Opioids affect the body’s systems that control breathing and sleeping, suppressing neurological signals that tell the body it’s not getting enough oxygen. The heart rate may slow, causing the individual to have sudden cardiac arrest, and the lungs may barely be working. This lack of oxygen causes brain damage if swift action isn’t taken, and the individual may begin to experience seizures.
In some cases, the overdose can include pulmonary edema, which occurs when fluid leaks into the lungs. The person may begin to foam at the mouth. Because opioids can suppress the individual’s gag reflex, the individual may choke.