Schizophrenia affects a relatively small share of the population — in the United States, an estimated 0.25% to 0.64% of people, according to the National Institute of Mental Health (NIMH). It’s a serious condition, but it’s treatable, and many people manage their symptoms and lead full lives with the right support. This page explains what schizophrenia is, how it shows up, how it’s diagnosed, and what causes it. If you or someone you love needs care, learn how FHE Health treats schizophrenia at our Deerfield Beach campus in South Florida.
What Is Schizophrenia?
Schizophrenia is a serious, chronic mental health condition that affects how a person thinks, feels, and behaves. According to the National Institute of Mental Health (NIMH), it is a type of psychosis — a loss of contact with reality — and can involve delusions, hallucinations, and disorganized thinking and behavior. Without treatment, schizophrenia can seriously affect a person’s safety, health, and ability to manage everyday life.
Types and Related Schizophrenia Spectrum Disorders
While schizophrenia is often discussed as a single condition, it exists within a broader category known as schizophrenia spectrum and other psychotic disorders. These conditions share similar features — disruptions in thinking, perception and behavior — but vary in duration and severity.
Some related disorders include:
- Schizoaffective disorder. Combines symptoms of schizophrenia, such as hallucinations or delusions, with mood disorder symptoms like depression or bipolar disorder.
- Schizophreniform disorder. Presents with symptoms similar to schizophrenia but lasts a shorter time, typically one to six months. Some people go on to develop schizophrenia, while others recover fully.
- Brief psychotic disorder. Sudden, short-term episodes of psychosis that often resolve within a month and may be triggered by stress or trauma.
- Delusional disorder. Persistent delusions without the broader range of symptoms seen in schizophrenia, such as significant cognitive impairment or disorganized speech.
Understanding these distinctions helps clinicians develop more accurate diagnoses and appropriate care plans.
Symptoms of Schizophrenia

Schizophrenia shows up through different sets of symptoms from person to person, which can make it difficult to diagnose. There’s no single behavior that signals someone might be developing the illness.
Here are the most common schizophrenia symptoms:
- Hallucinations and delusions. People with schizophrenia might have an alternate perception of reality and experience extreme paranoia. They might also hear, see or smell things that aren’t there, which can lead to unpredictable behavior.
- Negative symptoms. This is an umbrella term for a decrease in a person’s physical and mental abilities. These symptoms are common among people with schizophrenia, who can have difficulty communicating or performing basic daily tasks.
- Cognitive impairment. Schizophrenia tends to worsen memory and cognitive function. As a result, many people with schizophrenia lack the awareness needed to realize that their condition has changed.
These symptoms are fairly broad, which makes schizophrenia notoriously difficult to diagnose. Cognitive impairment and negative symptoms can be misdiagnosed as simpler, more common conditions like anxiety, depression or a variety of other disorders.
How Schizophrenia Is Diagnosed
Diagnosing schizophrenia involves a comprehensive evaluation rather than a single test. Mental health professionals rely on clinical assessments, medical history and observed behavior over time.
A diagnosis typically includes:
- A detailed psychiatric evaluation to assess symptoms like hallucinations, delusions and disorganized thinking
- A review of personal and family medical history
- Ruling out other potential causes, such as substance use or medical conditions
- Ongoing observation to confirm that symptoms persist for at least six months, including at least one month of active symptoms
Because symptoms can overlap with other mental health conditions, an accurate diagnosis often takes time and careful monitoring.
How Common Is Schizophrenia?
Schizophrenia is one of the less common mental health conditions, which is part of the reason the treatment community is continually making new discoveries about it.
In the United States, NIMH estimates that between 0.25% and 0.64% of people have schizophrenia or a related psychotic disorder. Worldwide, the World Health Organization estimates that about 24 million people — roughly 1 in 300 — live with the condition.
For comparison, schizophrenia is far less prevalent in the United States than many other mental health conditions, including generalized anxiety disorder, social anxiety disorder, post-traumatic stress disorder and depression.

Causes and Risk Factors of Schizophrenia
Schizophrenia doesn’t have a single known cause. It’s believed to result from a combination of genetic, biological and environmental factors. Contributing factors may include:
- Genetics. A family history of schizophrenia or other psychotic disorders may increase the likelihood of developing the condition, though it isn’t a guarantee.
- Brain chemistry and structure. Imbalances in neurotransmitters, particularly dopamine and glutamate, are thought to play a role, and differences in brain structure and function have been observed in some people with schizophrenia.
- Environmental factors. Exposure to viruses, malnutrition before birth, complications during pregnancy or significant stressors later in life may contribute to risk.
- Substance use. Using certain substances, especially during adolescence or early adulthood, can increase the risk of triggering psychotic episodes in people who are already vulnerable.
When Does Schizophrenia Develop?
Schizophrenia is most often diagnosed from the late teens to the early thirties, and it tends to emerge earlier in men than in women. This is a time when change is common in a person’s lifestyle and habits, which can make it harder to notice when behavior starts to shift because of mental illness rather than typical development.
Subtler changes in thinking, mood and social relationships often precede a formal diagnosis, sometimes by years.
Prodromal Schizophrenia
In people with schizophrenia, the years before diagnosis are known as the prodromal period. In teens, prodromal schizophrenia can cause social withdrawal, a change in grades and behavior, and other symptoms. The challenge with early diagnosis is that adults can dismiss these symptoms as typical teenage behavior.
With this in mind, if a young person shows these behaviors alongside a family history of psychosis, doctors may recommend additional evaluation to catch the signs of schizophrenia before it becomes more advanced.
Co-Occurring Disorders
Schizophrenia often occurs alongside other mental health or substance use disorders. These co-occurring conditions can complicate diagnosis and treatment if they aren’t addressed together.
Common co-occurring conditions include:
- Substance use disorders
- Depression
- Anxiety disorders
- Post-traumatic stress disorder (PTSD)
People with schizophrenia are also more likely to receive a dual diagnosis alongside other conditions, such as addiction. When that happens, the underlying issue can be more severe and harder to treat successfully. Using psychoactive and hallucinogenic drugs (LSD, for example) may also raise a person’s risk of developing schizophrenia later.
How Schizophrenia Is Treated

Schizophrenia is treatable. Care typically combines antipsychotic medication with therapy, and may include residential or outpatient support depending on symptom severity. For a full look at how FHE Health approaches care — including psychiatric evaluation, medication management, individual and group therapy, and step-down support — see our schizophrenia treatment page.







