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Home > Experience Blog > Does Weed Kill Brain Cells?

June 24, 2025 By Kristina Robb-Dover

Does Weed Kill Brain Cells?

Does weed kill brain spells?

Marijuana has been legalized in 24 states for recreational purposes, and this is likely to increase in the future, with many other states already decriminalizing the substance or allowing it for medicinal use. This normalization has led to some people wondering if weed is truly safe and what effect it can have on the body — specifically the brain. So, does weed kill brain cells? Experts don’t yet have a clear answer to this question, but there is a growing body of research that shows how cannabis use can affect brain health. In this article, we explore what the research says about marijuana use and brain function, the short- and long-term effects of weed, and why responsible use matters.

What Research Says About Cannabis and Brain Health: Does Smoking Weed Kill Brain Cells?

While there’s no clear evidence that marijuana kills brain cells, THC — which is the active component in weed that makes you feel high — can impair brain cell function. This is especially prominent in areas related to memory and attention. This can have a negative impact on cognitive function and a person’s ability to learn.

Some studies have also shown that long-term, heavy use of cannabis may result in changes to the brain structure. These changes were more prominent in adolescent users who started using marijuana at an early age. The effect of weed on brain structure and function may also depend somewhat on the strain. Higher-potency strains have a stronger effect on the body and brain and may cause more damage with long-term use.

Age, Frequency, and Brain Development Risks

The age and health of the person, how often cannabis is used, and how long cannabis has been used can impact the risks to the brain. Here are some facts to be aware of:

  • Younger users may have an increased risk of cognitive impairments from marijuana use. This can result in having difficulty in school and potentially even lower IQ scores with sustained use.
  • Early cannabis use may impact brain development. The human brain doesn’t fully develop until around age 25, which means that using marijuana before this time could have a permanent effect on the brain’s structure and function.
  • A person’s genetics and overall health can also play a role. Someone who has a family history of mental health issues or addiction may be more susceptible to substance use. Someone with existing health conditions may also see increased negative effects from weed use if the body is unable to metabolize the substance as normal.

While those who use marijuana for medicinal purposes may be at a lower risk of these side effects because they are under the guidance and supervision of a health care provider, recreational users don’t usually benefit from the same oversight. This can make it harder to weigh the risks against the potential benefits and recognize when substance use is becoming problematic.

Short-Term vs. Long-Term Cognitive Effects

Cannabis use can have both short- and long-term effects on the brain and cognitive function. Being aware of these effects can help you know what’s normal and what indicates problematic substance use that may require treatment.

Short-Term Effects

These short-term effects of marijuana use typically only occur in the 24 hours after use. They may be more intense immediately after use and then slowly dissipate.

  • Altered perception of time. Weed can distort a person’s sense of time, often making it seem like time is passing much more slowly than normal.
  • Difficulty making decisions. Because marijuana use can slow down cognitive processes, it can make it harder for someone to make decisions. They may feel like their brain is working slower than normal or like they can’t filter through options to make a choice.
  • Issues with short-term memory. Marijuana can affect the hippocampus area of the brain, which is responsible for memory. This can make it harder for the person to remember what just happened.
  • Poor coordination and motor skills. Marijuana decreases balance and motor coordination, which may result in the person having difficulty walking or moving, or they may feel like they’re trying to walk through water or that the world is moving around them.
  • Shorter attention span. A reduced ability to concentrate can be a side effect of marijuana use.

The intensity and duration of these symptoms can largely depend on the strain and potency of the marijuana and the person’s tolerance.

Long-Term Effects

When cannabis use is heavy or the person has been using for many years, it can eventually lead to lasting cognitive changes, such as:

  • Changes in brain structure. Heavy marijuana users are more likely to experience changes in the areas of the brain responsible for functions such as memory and decision making.
  • A lower IQ score. Those who start using marijuana in adolescence may experience lower IQ scores later on in adulthood.
  • Increased risk of dementia. Long-term cannabis use may be a risk factor for dementia and other memory-related conditions.
  • Slower reaction and processing times. Chronic marijuana users may have difficulty processing information quickly or responding to questions or stimuli with an appropriate reaction time.
  • Problems with memory and learning capacity. Using marijuana over the long term may decrease a person’s memory capacity and make it more challenging to learn new information.

The long-term effects of marijuana can have a significant impact on daily functioning and quality of life. If you or someone you love is experiencing these symptoms, it may be time to seek treatment.

The Importance of Responsible Use and Monitoring

If you’re going to use marijuana — whether for recreational or medicinal purposes — it’s important to do everything you can to make it as safe as possible. Never drive, operate machinery, or engage in any tasks that require intense focus while under the influence of marijuana or another substance.

Consider the potency of the strain you’re using and how the dosage and method of consumption may impact the strength of the side effects. It may help to track how frequently you’re using marijuana and how much you’re using at a time so that you have a clear record and can identify if substance use becomes a problem. It can also be beneficial to record how the marijuana is affecting you, such as how it changes your mood or ability to focus. This can make it easier to identify any potential negative side effects and can be a valuable source of information when seeking treatment.

When to Seek Help for Cannabis Use Issues

Signs of problematic marijuana use include strong cravings, experiencing withdrawal symptoms, trying to quit but not being able to, and continuing to use marijuana despite negative repercussions, such as poor work performance or relationship challenges.

A health care professional can look at the amount and frequency of your marijuana use as well as the symptoms you’re experiencing and help you come up with a treatment plan. This may include approaches like cognitive behavioral therapy (CBT) or prescribing medications. If cannabis use has started to negatively affect your life or your loved ones are expressing their concern, it may be time to get help.

Filed Under: Experience Blog

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About Kristina Robb-Dover

Kristina Robb-Dover is a content manager and writer with extensive editing and writing experience... read more

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