Drug Profile: Procentra

Drug Profile - Procentra

“ProCentra” is the brand name for “dextroamphetamine sulfate,” which acts as a central nervous stimulant. Dextroamphetamine (a.k.a. “d-amphetamine”) is one of two active forms of the synthetic compound “amphetamine,” and is also the stronger of these two forms (the other being “levo(l)-amphetamine”).

Amphetamines were developed as far back as the 1800’s when Romanian chemist Lazar Edeleanu synthesized the drug. Then, in 1929, biochemist Gordon Alles discovered the physiological activity of “beta-phenyl-isopropylamine” (soon to be officially known as amphetamine). By 1935, the medical community had become aware of amphetamines’ stimulating properties and the potency of one amphetamine in particular: d-amphetamine.

Shortly thereafter, Smith, Kline, and French, now known as GlaxoSmithKline, introduced d-amphetamine-containing tablets under the trade name “Dexedrine.” Meanwhile, according to the Library of Medicine, as early as 1937, the American Medical Association had approved advertising the amphetamine “Benzedrin Sulfate” for narcolepsy, attention deficit disorders and even depression.

What is ProCentra?

Drug profile on ProcentraProCentra is in a class of drugs used as central nervous stimulants for the treatment of attention deficit disorder with hyperactivity (ADHD) and narcolepsy. Other brand names of d-amphetamine are the aforementioned Dexedrine or “Zenzedi.” ProCentra is one of the most popular short-acting stimulant prescription drugs, along with two other well-known brand names “Adderall” and “Ritalin.”

The drug is considered a DEA Schedule II Controlled Substance, which means it has a “high potential for abuse” and “may lead to severe psychological or physical dependence.” Because of their stimulating effects, the drugs in this class are often misused. D-amphetamine is known on the street as “dex,” “bennies,” or “uppers.”

ProCentra – How It Is Prescribed

ProCentra is available in a clear, bubblegum–flavored liquid solution that is sugar-free. It is packaged in 16 fluid oz. bottles, with each 5mL containing 5 mg of dextroamphetamine. The bubblegum-flavored liquid makes it more palatable to pediatric patients with ADHD who may not be able to swallow tablets. The oral solution should be administered using a measuring device.

How Does it Work?

Common Questions about ProCentraProCentra works by releasing specific natural substances in the body like adrenaline, and raising cortisol levels and other stress hormones. The “fight or flight” response that it initiates also causes increased heart rate and blood pressure. Changes also include blood flow that is redirected into the muscles and away from the brain.

These changes increase your ability to stay focused, to control behavior and your ability to pay attention. It may help with listening skills as well as the ability to organize skills. ProCentra is also used to treat the sleeping disorder narcolepsy, because it can help you stay awake— but it should not be used to treat tiredness. Small doses can help you feel alert and refreshed. Often, however, the energy boost is followed by a “speed crash” and leaves the user feeling depressed and exhausted.

It’s always important to know how long a drug stays in your system, as taking too much can have serious side effects. The duration of the effect of ProCentra is four to eight hours. Like any medication, however, multiple factors can come into play regarding the duration of the effects. These factors can include age, metabolism, other medications and personal medical history.

ProCentra Rare and Common Side Effects

Some side effects may occur as a result of taking ProCentra. Not all of these side effects may occur, but if they do they may need medical attention. Rare ProCentra side effects include agitation, delusions and seeing, hearing or feeling things that are not there. Other side effects in which the incidence is not known include blurred vision, chest discomfort or pain, dizzinesss, headache, pounding in ears, twitching or twisting.

Some common psychiatric issues that may emerge with use of the drug may include abnormal behavior, aggression/hostility, anxiety and/or depression.

Some side effects of ProCentra tend to go away as the body adjusts to the medicine. These can include changes in taste, constipation, indigestion, bad, unusual or unpleasant aftertaste, dry mouth and redness of the skin.

ProCentra Addiction

Like any dextroamphetamine drug that is considered a prescription stimulant ProCentra can be highly addictive, particularly because of the “good” feelings it can induce:

  • Better focus
  • More energy
  • An increase in alertness
  • Suppressed appetite
  • Euphoria

Substance abuse occurs when the drug is taken in amounts above what is typically prescribed or via alternate methods of administration. Abuse of Procentra can lead to negative side effects, some of which can be serious and potentially deadly, including:

  • Difficulty thinking clearly
  • Impaired memory
  • Unhealthy weight loss and malnutrition
  • Hypertension (raised blood pressure)
  • Tachycardia (raised heart rate)
  • Impaired eyesight
  • Psychotic symptoms
  • Tremors
  • Seizures (highest risk in patients with seizure history)
  • Heart attack
  • Stroke
  • Death

Mixing any kind of d-amphetamine with alcohol can be dangerous and is not recommended. Combining the stimulatory effects of the drug with the depressant effects of alcohol can cause elevated heart rate, high blood pressure and other negative cardiovascular effects. The mixing of these two substances is strongly discouraged.

Treatment for the Drug ProCentra

Facts about ProCentraProcentra’s addictive properties can mean that users experience difficult withdrawal symptoms and even medical complications when they try to come off the drug. For this reason, detoxing cold turkey at home is never recommended. A medically supervised detox, as part of an inpatient and outpatient drug rehab program, can help ease the withdrawal process, ensuring that users are safe and medically monitored.

Symptoms of Procentra withdrawal can include:

  • Intense dextroamphetamine cravings
  • Difficulty concentrating
  • Disturbed sleep patterns
  • Fatigue
  • Anhedonia (inability to experience pleasure)
  • Depression
  • Paranoia
  • Physical and mental exhaustion

During a professional detox, caregivers may administer medications to relieve discomfort from symptoms like depression and insomnia. For example, sleep is often an issue during dextroamphetamine withdrawal. In these cases, medical professionals may prescribe medications such as Benadryl, hydroxyzine (Vistaril), or an antidepressant like trazodone or mirtazipine (which treats both insomnia and depression).

In some cases, addiction professionals may schedule a gradual taper in order to help the patient slowly wean off the drug.

Going off dextroamphetamine without guidance can pose serious risks including heart problems and stroke. It’s best to seek professional guidance for the safest and most comfortable detox process.

Are You Concerned About ProCentra Addiction?

If you are concerned that your child, teen or even yourself has become physically and psychologically dependent on ProCentra, please know that you don’t have to fight this drug addiction alone. Our compassionate and knowledgeable counselors are standing by 24/7 to help. Contact us today, and let us help you or your loved one navigate the difficult road to recovery.

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